Find Vacation Rentals .com offers these Panhandle Florida vacation rentals directly from their owner or manager. Accommodations include vacation homes, condo rentals, villa rentals, and beach rentals. Book directly with the owner or manager and save. Renting a vacation rental is simple, learn how. Popular destinations in the Florida Panhandle include Destin, Ft. Walton Beach, Panama City Beach, Santa Rosa Beach, Seagrove Beach and many more